Axon voltage-clamp simulations. III. Postsynaptic region
نویسندگان
چکیده
منابع مشابه
Nonuniform response in the squid axon membrana under voltage-clamp.
TASAKT, I. AND C. S. SPYROPOULOS. Nonunijorm response in the squid axon membrane under ‘voltage-clamp.’ Am. J. Physiol. 193(2): 309-317. 1958.-By cooling a portion of the squid giant axon at a time, it was shown that the repetitive membrane currents observed under the so-called voltageclamp conditions derived from the main portion of the ‘clamped’ axon membrane and not from the lateral unclampe...
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The sucrose-gap method introduced by Stämpfli provides a means for the application of a voltage clamp to the lobster giant axon, which responds to a variety of different experimental procedures in ways quite similar to those reported for the squid axon and frog node. This is particularly true for the behavior of the peak initial current. However, the steady state current shows some differences....
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,4BSTRACT TASAKI, I. AND C. S. SPYROPOULOS. Membrane conductance and currentvoltage relation in the squid axon under ‘voltage-clamp.’ &L-The conductance of the squid axon membrane under ‘voltage-clamp’ was measured by superposing a sinusoidal wave upon rectangular clamping voltage pulses. It was possible to determine the time course of the emf of the membrane under ‘voltage-clamp’ on a single p...
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The voltage-clamp electrophysiology method is the gold standard for measuring the function of ion channels. In the past, this technique has had limited applicability in pharmaceutical drug discovery because of its low throughput, steep learning curve, and challenges in standardization of the experiments. Recently, new electrophysiology platforms have been developed, which are based on the use o...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1975
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(75)85790-0